导师简介
一、教育背景及工作经历:
2007−2011 WilliamHill中文 学士 导师:蒋忠良
2011−2016 中国科学院上海有机化学研究所 博士 导师:游书力
2017−2021 美国加州理工学院 博士后 合作导师:Gregory C. Fu
2021−2023 WilliamHill中文高等研究院、william威廉中文 特聘研究员
2023−今 william威廉中文 准聘教授
二、职务和社会服务兼职:
2024−今 上海市虹口区第十届青联委员
2024−2025 WilliamHill中文国豪书院 副院长(挂职)
三、研究方向:
有机合成;过渡金属催化;不对称催化;自由基化学
四、荣誉与奖励:
2022 国家海外高层次人才引进计划(青年)
2021 上海海外高层次人才引进计划(青年)
2021 WilliamHill中文青年百人计划
五、代表性论文
Publications at Tongji:
2025:
6. Zhang, L.-L.; Li, L.-J.; Wang, N.; Yu, H.; Yang, Z.-P.* Enantioselective Radical‒Radical Cross-Couplings of β-Hydroxy Amides and N-Hydroxyphthalimide Esters via Ni/Photoredox Catalysis. J. Am. Chem. Soc. 2025, 147, doi:10.1021/jacs.5c10963.
5. Li, L.-J.; Zhang, J.-C.; Tang, J.-Y.; Yu, H.; Yang, Z.-P.* Acyclic Quaternary Stereocenters via Catalytic Asymmetric Cross-Couplings with Unactivated Alkyl N-Hydroxyphthalimide Esters. Angew. Chem. Int. Ed. 2025, 64, e202506883.
4. Zhang, L.-L.;† Gao, Y.-Z.;† Wang, N.; Yu, H.; Shen, S.-J.; Duanmu, K.;* Yang, Z.-P.* Enantioconvergent deoxygenative reductive cross-coupling of lactic acid derivatives. Sci. China Chem. 2025, 68, doi:10.1007/s11426-025-2666-y.
2024:
3. Chen, X.; Ping, Q.;* Lu, Q.; Yang, Z.; Wang, L.; Li, Y. Insight into the effect of CaO2 addition on the prevalence and removal of antibiotic resistance genes during anaerobic sludge fermentation under ambient conditions. J. Environ. Chem. Eng. 2024, 12, 113534.
2. Zhang, L.-L.;† Gao, Y.-Z.;† Cai, S.-H.; Yu, H.; Shen, S.-J.; Ping, Q.; Yang, Z.-P.* Ni-catalyzed enantioconvergent deoxygenative reductive cross-coupling of unactivated alkyl alcohols and aryl bromides. Nat. Commun. 2024, 15, 2733.
1. Li, L.-J.; Zhang, J.-C.; Li, W.-P.; Zhang, D.; Duanmu, K.; Yu, H.; Ping, Q.; Yang, Z.-P.* Enantioselective Construction of Quaternary Stereocenters via Cooperative Photoredox/Fe/Chiral Primary Amine Triple Catalysis. J. Am. Chem. Soc. 2024, 146, 9404−9412.
Selected Publications Prior to Tongji:
1. Yang, Z.-P.;† Dylan J. F.;† Fu, G. C.* Asymmetric Synthesis of Protected Unnatural α‑Amino Acids via Enantioconvergent Nickel-Catalyzed Cross-Coupling. J. Am. Chem. Soc. 2021, 143, 8614−8618.
2. Yang, Z.-P.;† Dylan J. F.;† Fu, G. C.* The Asymmetric Synthesis of Amines via Nickel-Catalyzed Enantioconvergent Substitution Reactions. J. Am. Chem. Soc. 2021, 143, 2930−2937.
3. Yang, Z.-P.; Fu, G. C.* Convergent Catalytic Asymmetric Synthesis of Esters of Chiral Dialkyl Carbinols. J. Am. Chem. Soc. 2020, 142, 5870−5875.
4. Yang, Z.-P.;† Jiang, R.;† Wu, Q.-F.; Huang, L.; Zheng, C.; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Benzene Derivatives. Angew. Chem. Int. Ed. 2018, 57, 16190−16193.
5. Yang, Z.-P.; Jiang, R.; Zheng, C.; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Alkylation of Hydroxyquinolines: Simultaneous Weakening of the Aromaticity of Two Consecutive Aromatic Rings. J. Am. Chem. Soc. 2018, 140, 3114−3119.
6. Yang, Z.-P.; Zheng, C.; Huang, L.; Qian, C.; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Benzoxazoles, Benzothiazoles, and Benzimidazoles. Angew. Chem. Int. Ed. 2017, 56, 1530−1534.
7. Yang, Z.-P.; Wu, Q.-F.; Shao, W.; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Pyridines, Pyrazines, Quinolines, and Isoquinolines. J. Am. Chem. Soc. 2015, 137, 15899−15906.
8. Yang, Z.-P.; Wu, Q.-F.; You, S.-L.* Direct Asymmetric Dearomatization of Pyridines and Pyrazines by Iridium-Catalyzed Allylic Amination Reactions. Angew. Chem. Int. Ed. 2014, 53, 6986−6989.
9. Tong, X.; Yang, Z.-P.; Del Angel Aguilar, C. E.; Fu, G. C.* Iron-Catalyzed Reductive Cross-Coupling of Alkyl Electrophiles with Olefins. Angew. Chem. Int. Ed. 2023, 62, e202306663.
10. Wang, Z.; Yang, Z.-P.; Fu, G. C.* Quaternary stereocentres via catalytic enantioconvergent nucleophilic substitution reactions of tertiary alkyl halides. Nat. Chem. 2021, 13, 236−242.
11. Zhang, X.; Yang, Z.-P.; Huang, L.; You, S.-L.* Highly Regio- and Enantioselective Synthesis of N-Substituted 2-Pyridones: Iridium-Catalyzed Intermolecular Asymmetric Allylic Amination. Angew. Chem. Int. Ed. 2015, 54, 1873−1876.
热忱欢迎对有机合成等领域感兴趣的有志青年加盟,开展创新实验、本科毕设、硕士博士攻读及博士后研究!